Glycine Powder – USP Grade

(12 Reviews)

$35.00 — or subscribe to save 10%

What it does for you:

  • Deeper, more restful sleep and calmer evenings, so you wake up clearer
  • Restful sleep support — deeper, more settled nights
  • Supports calm and relaxation — an easy way to wind down in the evening
  • Wake up more rested, clearer in the morning, even after a short night
  • Collagen building block — about one in every three amino acids in collagen is glycine
  • Naturally sweet — mixes easily into water, tea, or any drink
  • USP Grade, 99.9% pure · made in the USA · one ingredient · scoop included
  • A bioenergetic favorite — glycine balances a meat-heavy diet and helps you wind down from stress

In a small study of healthy adults, glycine taken with sugar was linked to a gentler post-meal glucose response.

Powder makes the amount used in the sleep studies easy — no handful of capsules. Just glycine. No fillers or additives. 60-day no hassle returns.

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Deeper, more restful sleep and calmer evenings, so you wake up clearer.

  1. Restful sleep support — many people take it in the evening for deeper, more settled sleep.
  2. Supports calm and relaxation — glycine is one of the body’s own calming signals.
  3. Wake up more rested and clearer in the morning, even after a short night.
  4. Collagen building block — about one in every three amino acids in collagen is glycine.
  5. Antioxidant support — glycine is one of three building blocks the body uses to make glutathione, its own antioxidant.
  6. Naturally sweet, mixes easily — stir it into water, tea, coffee, or milk.

Why it fits bioenergetic living. Calm, restful nights are where energy gets rebuilt. Glycine is the amino acid that gelatin and bone broth are richest in, and many people eating for energy add it to balance a diet heavy in muscle meat. One ingredient, nothing else.

Why powder? The sleep research used a few grams before bed. In powder that’s a couple of scoops in a drink — no handful of capsules. (Exact amounts live in Suggested Use.)

USP Grade glycine, 99.9% pure, made in the USA. One ingredient, no fillers or additives. Packed in a bag with a scoop.

As one customer puts it: “Helps my sleep. I sleep deeper and for a longer period at night.”

Available: 250 g and 1000 g. 60-day no hassle returns.

Lab tested: View the latest Certificate of Analysis (PDF)

How to start: Begin with 1 level scoop (about 1 g) once a day, mixed in water or any drink. Many people take it in the evening or before bed. Stay there for a few days and notice how you sleep and how you feel the next day.

Raising slowly: If you want more, add one scoop every few days, up to 3 scoops a day (about 3 g). Take them together before bed or spread them through the day. Stop wherever it feels right for you. More is not automatically better.

If it feels like too much: Some people notice an upset stomach or loose stools, or feel too drowsy or groggy the next morning, when the amount is higher than they need. If that shows up, take less — go back to what felt comfortable — and talk with your healthcare provider.

Practical notes:

  • Naturally sweet. Stir it into water, tea, coffee, warm milk, or juice. It dissolves easily.
  • Taking it during the day? Start with one scoop and see how you feel — some people find it relaxing.
  • One level scoop holds about 1 g.
  • Store cool, dark, and dry; keep the bag sealed.

As a dietary supplement only. Talk with your healthcare provider before use — especially if you take medication (including anything for sleep or mood), are pregnant or nursing, or are unsure what’s right for you.

Glycine (USP Grade)

Other Ingredients: None

99.9% Pure • Made in USA

Serving Size: 1 level 1.25cc scoop (1 gram)
Servings Per Container: 250 (250 g) | 1000 (1000 g)

Amount Per Serving:
Glycine — 1 g
*Daily Value not established.

• Lab tested: View the latest Certificate of Analysis (PDF)
• USP Grade
• Sourced from USA
• Tested for purity and potency
• 99.9% pure
• No fillers or additives
• Packaged in a bag with scoop included

How do I start taking glycine? Begin with 1 level scoop (about 1 g) once a day in water or any drink. Many people take it in the evening or before bed. Stay there for a few days and notice how you sleep and feel.

Can I raise the amount? Yes — add one scoop every few days, up to 3 scoops a day (about 3 g). Stop wherever it feels right. More is not automatically better.

What if it feels like too much? Some people notice an upset stomach or loose stools, or feel too drowsy or groggy the next morning. Take less — go back to what felt comfortable — and talk with your healthcare provider.

When is the best time to take it? For sleep, in the evening or before bed. During the day, start with one scoop and see how you feel.

What does it taste like? Lightly sweet. That’s just how glycine tastes — nothing is added. It mixes easily into hot or cold drinks.

How is glycine different from collagen or gelatin? Collagen and gelatin are whole proteins, and about a third of their amino acids are glycine. Glycine powder is that one amino acid on its own, so a small scoop gives you a set amount. Many people use both, like our Collagen Hydrolysate Powder (Grass-Fed Beef).

Why do people pair glycine with meat? Muscle meat is high in methionine and lower in glycine than the skin, bone, and broth people used to eat with it. In the bioenergetic community, many people add glycine or gelatin to bring that mix closer to whole-animal eating.

What does USP Grade mean? It meets the identity and purity standards set by the United States Pharmacopeia (USP) for glycine. Ours is 99.9% pure.

What’s in it? Glycine only. No fillers or additives. Made in the USA and packed in a bag with a scoop.

What do people take with it? Customers often buy it with Taurine Powder – USP Grade (Ajinomoto) and Magnesium Chloride Capsules. If you take prescription medication, ask your healthcare provider.

How should I store it? Cool, dark, and dry, with the bag sealed.

Glycine is the smallest amino acid. The body uses it as a calming signal and as a main building block of collagen and glutathione. Taken before bed, it has been studied for sleep quality.

Restful sleep and calm — in customers’ words

  • “Helps my sleep. I sleep deeper and for a longer period at night.” — Jim D.
  • “I am taking this before bed and it is helping sleep somewhat.” — Robert T.
  • “In the short time I use it now I notice a relaxation right after using it” — Bart L.

Restful sleep support

  • Better sleep quality Bannai & Kawai (2012). Journal of Pharmacological Sciences, 118(2), 145–148. PMID 22293292. In adults who weren’t sleeping well, glycine before bed improved how well they felt they slept. Lab work points to one reason: glycine helps the body shed heat, and a small drop in core temperature is one of the body’s natural cues for sleep.
  • More rested next day Bannai, Kawai, Ono, Nakahara & Murakami (2012). Frontiers in Neurology, 3, 61. PMID 22529837 · PMC3328957. Healthy adults slept 25% less than usual for three nights. With 3 g of glycine before bed, they felt less tired the next day and did better on an alertness test than with placebo.
  • Why it may help Kawai, Sakai, Okuro, Karakawa et al. (2015). Neuropsychopharmacology, 40(6), 1405–1416. PMID 25533534. In rats, glycine gently lowered core body temperature and supported sleep through the brain’s body-clock area, which fits the heat-shedding idea above.

Collagen building block

  • The body may run short Meléndez-Hevia, De Paz-Lugo, Cornish-Bowden & Cárdenas (2009). Journal of Biosciences, 34(6), 853–872. PMID 20093739. About a third of collagen is glycine. Adding up how much glycine an adult makes (about 3 g a day) and eats (1.5–3 g), the authors found it may fall about 10 g a day short of what the body uses, collagen included. They concluded glycine is worth taking as a supplement.

Antioxidant support

  • Glutathione building block Sekhar, Patel, Guthikonda, Reid, Balasubramanyam, Taffet & Jahoor (2011). American Journal of Clinical Nutrition, 94(3), 847–853. PMID 21795440 · PMC3155927. Older adults had less glycine and less glutathione, the body’s own antioxidant, than younger adults. After two weeks of glycine plus cysteine, their glutathione rose to match the younger group, and markers of oxidative stress went down.

Post-meal glucose

  • Gentler post-meal glucose Gannon, Nuttall & Nuttall (2002). American Journal of Clinical Nutrition, 76(6), 1302–1307. PMID 12450897. In 9 healthy adults, taking glycine (about 1 mmol per kg of lean body mass) with 25 g of glucose cut the post-meal glucose response by more than half compared with glucose alone. Insulin response was not significantly different.

Naturally sweet, one ingredient

  • “Super taste and mixes in liquids without clumping!” — Paula S.
  • “Double packaging helps to keep the light out and the contents fresh.” — Shaun G.
  • One ingredient USP Grade glycine, 99.9% pure, made in the USA. No fillers or additives.

Bioenergetic & low-toxin perspective

Ray Peat wrote about glycine as a calming, protective amino acid, and about getting it the traditional way, from gelatin.

“Glycine is recognized as an ‘inhibitory’ neurotransmitter, and promotes natural sleep.” — Ray Peat, “Gelatin, stress, longevity” (https://raypeat.com/articles/articles/gelatin.shtml)

“A generous supply of glycine/gelatin, against a balanced background of amino acids, has a great variety of antistress actions.” — same article

Studies Peat cited in “Gelatin, stress, longevity” (https://raypeat.com/articles/articles/gelatin.shtml):
Zhong Z, Wheeler MD, Li X, et al. (2003). L-Glycine: a novel antiinflammatory, immunomodulatory, and cytoprotective agent. Curr Opin Clin Nutr Metab Care 6(2):229-40. PMID 12589194. A review of glycine's calming, cell-protective roles.

Note: The papers above study glycine in general, not this product directly. The sleep studies were small human trials; the others are lab, animal or review papers. The glutathione study paired glycine with cysteine. Customer comments are individual experiences. This information is for educational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Talk with your healthcare provider.

Consult your healthcare professional before use if you are pregnant, nursing, taking medication, or have a medical condition. Keep out of reach of children. Do not use if the bag is damaged or the seal is broken.

May cause drowsiness. If it makes you sleepy, do not drive or operate machinery after taking it.

Start with a low amount and increase as tolerated.

Store in a cool, dark, dry place. Keep tightly closed. Protect from heat.

*Statements made on this website have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Restful sleep support, calmer evenings, and waking up more rested even after a short night: that's why people choose our glycine.

A building block of collagen, and of glutathione, the body's own antioxidant. USP Grade, 99.9% pure, tested for purity and potency. Made in the USA. One ingredient — no fillers or additives. Naturally sweet and mixes easily. As one customer puts it, "Super taste and mixes in liquids without clumping!"

Two sizes, 250 g and 1000 g, each in a bag with a scoop. We've carried it since 2019. Family-owned, with fast shipping from the United States. 60-day no hassle returns.

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Customer Reviews

Jahaziel Alvarez
Rating: 5/5
Pure as snow
The best glycine I've had.
Fri Oct 16 2026 13:28:01 GMT+0000 (Coordinated Universal Time)
Jaya P BODDU
Rating: 5/5
Glycine.
Received as promised in time. I started using the same for the last one week. It is very good. Keeps up my energy levels and decreases stiffness and ache in my joints. I have enough stock for now. I would definitely reorder and recommend it.
Thu Jun 25 2026 22:54:13 GMT+0000 (Coordinated Universal Time)
Jim A Dunbar
Rating: 5/5
Helps my sleep. I sleep deeper and for a longer period at night. Wonderful product.
Wed Apr 17 2024 01:22:40 GMT+0000 (Coordinated Universal Time)
ROBERT TURNQUIST
Rating: 5/5
Glycine powder
I am taking this before bed and it is helping sleep somewhat. Thank you.
Wed Oct 18 2023 00:33:19 GMT+0000 (Coordinated Universal Time)
Shaun G.
Rating: 5/5
Quality Product
The picture made it appear to be larger than the package actually is, but it’s still a good amount of glycine within. Double packaging helps to keep the light out and the contents fresh. I add it to my energy drinks, which makes them fizz up, but doesn’t affect the taste in a bad way since the glycine is sweet.
Thu Dec 08 2022 09:25:13 GMT+0000 (Coordinated Universal Time)
marc baptie
Rating: 5/5
: GOOD-STUFF.
: GREAT-COMPANY.
Thu Jun 30 2022 00:28:39 GMT+0000 (Coordinated Universal Time)
Paula S.
Rating: 5/5
Great
Super taste and mixes in liquids without clumping!
Tue Aug 24 2021 00:45:11 GMT+0000 (Coordinated Universal Time)
James
Rating: 5/5
Elite Glycine
Best powder I’ve seen/had. .. top of the line quality. Enjoy!
Thu May 13 2021 00:49:46 GMT+0000 (Coordinated Universal Time)
Barry Nutter
Rating: 5/5
Glycine Powder USP Grade
Fri Feb 12 2021 20:52:39 GMT+0000 (Coordinated Universal Time)
Rouzbeh Zamyadi
Rating: 5/5
Great
Excellent reliable source and great service!
Thu Dec 17 2020 16:04:36 GMT+0000 (Coordinated Universal Time)